As my responsibilities at work increase, so does my need for organization. I've tried keeping To-Do lists in the past but they have always failed: either my busyness ends and I no longer have enough tasks to warrant a list or my structure is either too complicated or too simple and I can't keep up with it.
For the past few months I've been trying My Life Organized for task organization. It's definitely the best I've tried, much better than Outlook. My Life Organized allows you to enter your tasks in a dependent format, something Outlook does not allow (you have a tree of tasks, instead of just a list). Once you get all your tasks setup and entered, you can switch the view to "To-Do List" which shows all the next action tasks and items that are due soon. Also, being the geek I am, I appreciate the Pocket PC version (I haven't had it syncing under Vista yet - I plan on emailing them soon to find out why not - but I can just imagine being able to enter tasks on my PPC during meetings and syncing them afterwards). It's worth checking out the website if you are in the market for a new To-Do list organizer. The only downside would be the $70 price tag for the Professional bundle with the Pocket PC app. However, there is a free version, and they have other options that are cheaper, depending on your needs.
Also, over at 43 Folders, there's an article on writing To-Dos. The author gives some extremely helpful tips on creating To-Do items, pruning your list, finishing items that make you anxious, and much more. If nothing else, make sure you read the section on writing To-Dos ("Anatomy of a To-do"): he gives some great questions to ask yourself as you're creating your list. This is a 2 part article, so be sure to check out Part 2 even more great information!
Building a Smarter To-Do List, Part I | 43 Folders & Building a Smarter To-Do List, Part II